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基于Frankl意义治疗理论的生命意义干预对癌症患者影响的Meta分析
作者:
作者简介:

1．孙咪咪，广州中医药大学护理学院硕士在读。Email：18895656833@163.com
2．肖文莉，博士，广州中医药大学护理学院副教授，硕士生导师。Email：021095allison@gzucm.edu.cn

中图分类号:

R473.73；R48


Meta-analysis of Logotherapy-Based Meaning in Life Intervention Effects on Cancer Patients
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    摘要:

    目的 系统评价基于Frankl意义治疗理论的生命意义干预对癌症患者灵性、心理及生活质量的干预效果。方法 检索Medline、The Cochrane Library、Embase、Web of Science、CINAHL、中国生物医学文献数据库、中国知网、万方和维普数据库。采用RevMan 5.4进行Meta分析。结果 纳入9项随机对照试验，共1082例患者。结果显示，生命意义干预可改善癌症患者的生命意义感（SMD=-0.24，95% CI：-0.40~-0.07，P=0.006）、灵性健康（MD=-0.32，95% CI：-0.48~- 0.15，P=0.0001）、绝望感（SMD=-1.39，95% CI：-2.53~-0.24，P=0.02）、抑郁（SMD=-0.82，95% CI：-1.61~-0.03，P=0.04）；亚组分析显示，生命意义干预对癌症患者焦虑（SMD=-0.43，95% CI：-0.64~-0.23，P<0.0001）的改善效果优于常规护理；可提高实体肿瘤或非霍奇金淋巴瘤患者的生活质量（SMD=-0.60，95% CI：-0.88~-0.33，P<0.0001）。结论 基于Frankl意义治疗理论的生命意义干预可提高癌症患者的生命意义感、灵性健康，降低绝望感、抑郁水平，常规对照条件下可改善癌症患者的焦虑情绪，有效提高实体肿瘤或非霍奇金淋巴瘤患者的生活质量水平。

    Abstract:

    Objective To systematically evaluate the impact of meaning in life intervention, rooted in Frankl’s theory of logotherapy, on the spiritual, psychological and quality of life in cancer patients. Methods Databases including Medline, The Cochrane Library, Embase, Web of Science, CINAHL, CBM, CNKI, Wanfang Data and VIP were searched. RevMan 5.4 was used for meta-analysis.Results Nine randomized controlled trials involving 1082 patients were included. Meaning in life intervention enhanced meaning in life (SMD=-0.24, 95% CI:-0.40~-0.07, P=0.006), spiritual well-being (MD=-0.32, 95% CI:-0.48~- 0.15, P=0.0001), and reduced hopelessness (SMD=-1.39, 95% CI:-2.53~-0.24, P=0.02) and depression (SMD=-0.82, 95% CI:-1.61~-0.03, P=0.04) in cancer patients. Subgroup analysis revealed that the intervention was more effective in reducing anxiety (SMD=-0.43, 95% CI: -0.64~-0.23, P<0.0001) and improving the quality of life (SMD=-0.60, 95% CI:-0.88~-0.33, P<0.0001) for patients with solid tumors or non-Hodgkin’ s lymphoma. Conclusion Meaning in life intervention based on Frankl’s logotherapy theory significantly improved the meaning in life and spiritual well-being, and alleviated hopelessness and depression in cancer patients. The intervention also effectively reduced anxiety compared with usual care and enhanced the quality of life for patients with solid tumors or non-Hodgkin‘s lymphoma.

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孙咪咪,田霞,卢咏梅,周丽群,周晓君,彭蕴仪,肖文莉.基于Frankl意义治疗理论的生命意义干预对癌症患者影响的Meta分析[J].华人生死学,2023,(2):45-58

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